By car it's 40 minutes south east of Avignon and one hour north of Marseille Airport or the same distance due east of Nimes. We're off the N100, 3 kilometres above the regional market town of Apt.
The Eurostar from London travels directly to the old Avignon Station and the TGV from Paris makes the journey to the new Avignon TGV station in only 2h 45. If you're taking the train and booking a car make sure you match your car hire to your train station!